IPEX syndrome with membrano-proliferative nephrotic syndrome.

A two-month old male infant initially presented with cutaneous candidiasis. He is the second child of nonconsanguineous healthy parents whose first born is a bright six year old school girl. This boy was born at term following an uncomplicated antenatal period with a birth weight of 2.9 kg. He was exclusively breast fed for six months. Initial tests for immunodeficiency including full blood count, HIV screening, CD 3,4,8,19,16 subsets, serum IgG, IgM and IgA levels were normal. IgE levels were not assessed due to non-availability of facilities.